AUTHOR=Huo Kang , Shang Suhang , Wang Jin , Chen Chen , Dang Liangjun , Gao Ling , Wei Shan , Zeng Lingxia , Qu Qiumin 

TITLE=Trends on Prevalence, All-Cause Mortality, and Survival Status of Dementia Patients in Rural China Based on Pooling Analysis

JOURNAL=International Journal of Public Health

VOLUME=69

YEAR=2024

URL=https://www.ssph-journal.org/journals/international-journal-of-public-health/articles/10.3389/ijph.2024.1606786

DOI=10.3389/ijph.2024.1606786

ISSN=1661-8564

ABSTRACT=<sec><title>Objectives</title><p>No study has reported secular trends in dementia prevalence, all-cause mortality, and survival status in rural China.</p></sec><sec><title>Methods</title><p>We established two cohorts (XRRCC1 and XRRCC2) in the same region of China, 17 years apart, to compare dementia prevalence, all-cause mortality, and survival status, and performed regression analysis to identify associated factors.</p></sec><sec><title>Results</title><p>Dementia prevalence was 3.49% in XRRCC1 and 4.25% in XRRCC2, with XRRCC2 showing a significantly higher prevalence (OR = 1.79, 95%CI: 1.2–2.65). All-cause mortality rates for dementia patients were 62.0% in XRRCC1 and 35.7% in XRRCC2. Mortality in the normal population of XRRCC2 decreased by 66% compared to XRRCC1, mainly due to improved survival rates in women with dementia. Dementia prevalence was positively associated with age &gt;65, spouse-absent status, and stroke, and negatively associated with ≥6 years of education.</p></sec><sec><title>Conclusion</title><p>Dementia prevalence in rural China increased over 17 years, while mortality decreased. Major risk factors include aging, no spouse, and stroke, with higher education offering some protection.</p></sec>