AUTHOR=Vedachalam Srividya K. , Rajput Bhavesh L. , Choudhary Sushma , Narayanaswamy Darshan , Chandra Sharath , D. M. Pallavi , Rajagopal Padma M. , Dikid Tanzin TITLE=Kyasanur Forest Disease: An Epidemiological Investigation and Case-Control Study in Shivamogga, Karnataka, India-2022 JOURNAL=International Journal of Public Health VOLUME=69 YEAR=2024 URL=https://www.ssph-journal.org/journals/international-journal-of-public-health/articles/10.3389/ijph.2024.1606715 DOI=10.3389/ijph.2024.1606715 ISSN=1661-8564 ABSTRACT=Objective

Kyasanur Forest Disease (KFD) is a viral zoonosis reported from Karnataka, India. We investigated cases in the Shivamogga district, Karnataka, to describe the epidemiology and identify risk factors in the affected block in 2022.

Methods

A case was defined as a laboratory-confirmed KFD-positive resident of Shivamogga from 1 January-31 May 2022. We extracted the records of KFD cases from district surveillance. We conducted a 1:3 case-control study in the Thirthahalli block. We enrolled laboratory-confirmed KFD-positive Thirthahalli residents from January to May 2022 as cases, and residents without “fever with myalgia” as controls. We reported adjusted odds ratios (aOR) with 95% confidence intervals (CI).

Results

Shivamogga reported 35 cases, with a median age of 46 (4–75) years, of which 51% were men, and one death. Among 25 cases and 90 controls, knowledge of avoiding recent monkey death sites was low (cases = 0%, controls = 11%). Monkey death sites within 500 m [aOR = 8.6 (1.8–41.9)] and household tick exposure [aOR = 3.7 (1.3–10.7)] were independent risk factors.

Conclusion

This was a laboratory-confirmed cluster of KFD cases in Thirthahalli, with residence near a monkey death site and household tick exposure considered significant risk factors. We recommend evaluating monkey carcass disposal procedures and increasing awareness of tick protective measures.