AUTHOR=Feng Xiyu , Sarma Haribondhu , Seubsman Sam-Ang , Sleigh Adrian , Kelly Matthew 

TITLE=The Impact of Multimorbidity on All-Cause Mortality: A Longitudinal Study of 87,151 Thai Adults

JOURNAL=International Journal of Public Health

VOLUME=68

YEAR=2023

URL=https://www.ssph-journal.org/journals/international-journal-of-public-health/articles/10.3389/ijph.2023.1606137

DOI=10.3389/ijph.2023.1606137

ISSN=1661-8564

ABSTRACT=<p><bold>Objectives:</bold> To investigate associations between multimorbidity, socio-demographic and health behaviour factors, and their interactions (multimorbidity and these factors) with all-cause mortality among Thai adults.</p><p><bold>Methods:</bold> Associations between multimorbidity (coexistence of two + chronic diseases) and mortality between 2005 and 2019 were investigated among Thai Cohort Study (TCS) participants (<italic>n</italic> = 87,151). Kaplan-Meier survival curves estimated and compared survival times. Multivariate Cox proportional hazards models examined associations between risk factors, and interactions between multimorbidity, these factors, and survival.</p><p><bold>Results:</bold> 1,958 cohort members died between 2005 and 2019. The risk of death was 43% higher for multimorbid people. In multivariate Cox proportional hazard models, multimorbidity/number of chronic conditions, age, long sleep duration, smoking and drinking were all independent factors that increased mortality risk. Women, urbanizers, university education, over 20,000-baht personal monthly income and soybean products consumption lowered risk. The interactions between multimorbidity and these variables (except for female, urbanizers and soybeans intake) also had significant (<italic>p</italic> &lt; 0.05) impact on all-cause mortality.</p><p><bold>Conclusion:</bold> The results emphasise the importance of healthy lifestyle and reduced intake of alcohol and tobacco, in reducing premature mortality, especially when suffering from multimorbidity.</p>