AUTHOR=Hu Zhigang , Tian Yufeng , Song Xinyu , Hu Ke , Yang Ailan 

TITLE=Associations Between Incident Asthma With Comorbidity Profiles, Night Sleep Duration, and Napping Duration Trajectories: A 7-Year Prospective Study

JOURNAL=International Journal of Public Health

VOLUME=Volume 67 - 2022

YEAR=2022

URL=https://www.ssph-journal.org/journals/international-journal-of-public-health/articles/10.3389/ijph.2022.1604939

DOI=10.3389/ijph.2022.1604939

ISSN=1661-8564

ABSTRACT=Objectives: We aim to determine whether comorbidity profiles, night sleep duration and napping duration trajectories were associated with incident asthma in Chinese adults.
Methods: 7655 community-dwelling individuals were included in this study. Latent class/profile analysis(LCA/LPA) identified comorbidity profiles, night sleep duration and napping duration trajectories. Generalized additive model with binomial regression assessed the associations between incident asthma with sleep trajectories.  
Results: During 7-year follow-up, 205 individuals were newly diagnosed with asthma. LPA identified four trajectories of night sleep duration: dominant short(n=2480), dominant healthy-long(n=1405); long decreasing(n=1875); and short increasing(n=1895). We also found three trajectories of napping duration: short increasing(n=3746); stable normal(n=1379); and long decreasing(n=2530); and three comorbidity profiles: dominant heart diseases or risks(n=766); multiple disorders(n=758); and minimal or least disorders(n=6131). Compared with dominant short night sleep duration, three other trajectories were associated with significantly decreasing incident asthma. Minimal or least disorders profile was associated with the significant reduction of new-onset asthma than two other comorbidity profiles in dominant short night sleep duration.
Conclusions: Our findings suggested that dominant short night sleep duration trajectory potentially increases incident asthma in Chinese adults.